In the cohort study, the researchers used 2013 to 2021 nationwide registry data from Sweden and Denmark to assess suicidality, self-harm or depression among new users of either GLP-1 receptor agonists or sodium glucose cotransporter-2 (SGLT2) inhibitors
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[12:42] If you add to that that the microglia also influence quinolinic acid, serotonin, dopamine, and a host of other neurochemical pathways that then influence the neuroexcitatory sympathetic response, you've got sensory overwhelm, everything in the world seems disproportionately threatening, and you're hyper-alert
This protocol rapidly induced marked functional disability, in particular, a difficulty with maintaining body balance while rearing, an inability of the right forelimb to react (and thereby cuprizone-rats react only with one or no forelimb), and severely affected various brain areas [31]
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